striol (oestriol) Female Steroids Hormone Powder Estriol for Health Care 50-27-1 treat prostate cancer
A chemical derivative of estradiol, ethinyl estradiol with maximum dosage 200 μg, is a major component of hormonal contraceptive devices. Combined forms of hormonal contraception contain ethinyl estradiol and a progestin, which both contribute to the inhibition of GnRH, LH, and FSH, which accounts for the ability of these birth control methods to prevent ovulation and thus prevent pregnancy. Other types of hormonal birth control contain only progestins and no ethinyl estradiol.
Estriol
Synonyms: oestriol; 1,3,5(10)-Estratriene-3,16a,17b-triol
CAS: 50-27-1
EINECS: 200-022-2
Assay: 97.0%-102.0%, USP30.
Packing: foil bag or tin..
Delivery: Express courier.
Character: White crystalline powder.
Usage: A metabolite of Estradiol. An estrogenic metabolite considerably less potent than the hormone Estradiol. pharmaceutical material, Steroid hormone, estrogen.
Standards:USP27
COA:
TEST ITEMS |
SPECIFICATION |
RESULTS |
Description |
: White or Almost White Crystalline Powder |
white powder |
Identification |
: A.B. |
Positive |
Assay |
: 97.0~102.0% |
99.3% |
Specific Rotation |
: +101°~+105° |
+102.6° |
Loss On Drying |
: 1.0%max |
0.27% |
Melting Point |
: 153~157°C |
153.0~155.0°C |
Organic Volatile Impurities |
: meets the requirement. |
Conforms |
Related Substances |
: meets the requirement. |
Conforms |
Residual Solvents |
: meets the requirement. |
Conforms |
Particle Size |
: 100% ≤ 20 microns |
Conforms |
Conclusion |
The specification conform with USP30 standard |
Hormonal contraception:
A chemical derivative of estradiol, ethinyl estradiol with maximum dosage 200 μg, is a major component of hormonal contraceptive devices. Combined forms of hormonal contraception contain ethinyl estradiol and a progestin, which both contribute to the inhibition of GnRH, LH, and FSH, which accounts for the ability of these birth control methods to prevent ovulation and thus prevent pregnancy. Other types of hormonal birth control contain only progestins and no ethinyl estradiol.
Hormone replacement therapy:
If severe side effects of low levels of estradiol in a womans blood are experienced (commonly at the beginning of menopause or after oophorectomy), hormone replacement therapy may be prescribed. Such therapy is usually combined with a progestin to reduce the risk of endometrial cancer.
Estrogen therapy may be used in treatment of infertility in women when there is a need to develop sperm-friendly cervical mucus or an appropriate uterine lining. This is often prescribed in combination with clomifene.
Estrogen therapy can also be used to treat advanced prostate cancer, as well as to relieve symptoms of breast cancer.
Not all products are available worldwide. Estradiol is also part of conjugated estrogen preparations, such as Premarin, though it is not the major ingredient. (Premarin consists of a large number of estrogen derivatives. As the name indicates, it comes from pregnant mares urine.