English

Hubei HAKE Chemcial Co., Ltd

Hubei HAKE Chemcial Co., Ltd The difference between a product and a product is in the details

Home > Products > HGH Human Growth Hormone > MYOSTATIN Peptide Raw Steroid Powder Myostatin Human Growth Hormone 99.9% Purity
 

MYOSTATIN Peptide Raw Steroid Powder Myostatin Human Growth Hormone 99.9% Purity

  • MYOSTATIN Peptide Raw Steroid Powder Myostatin Human Growth Hormone 99.9% Purity
Place of Origin:
China
Brand Name:
MYOSTATIN
Certification:
SGS
Model Number:

MYOSTATIN

Min.Order Quantity:
10g
Price:
Negotiation
Packaging Details:
1kg/Aluminum foil bag
Delivery Time:
3-5 days after received your deposit
Payment Terms:
Western Union, MoneyGram,biycoin
Supply Ability:
1000kg/month
Contact Now
 

Product Description

MYOSTATIN Peptide HGH Human Growth Hormone Raw Materials Myostatin Human Growth
Detailed Product Description
Appearance: Powder Purity: 99.9%
Production Capacity: 1000kg/month Application: For Research
DeliveryTime: 3-5 Days After Received Your Deposit Storage: Keep Dry
Packing: Safe Discreet Packages Through Customers Package: 1kg/Aluminum Foil Bag

Products Description:

Myostatin

Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.

Animals either lacking myostatin or treated with substances that block the activity of myostatin have significantly more muscle mass. Furthermore, individuals who have mutations in both copies of the myostatin gene have significantly more muscle mass and are stronger than normal. Blocking the activity of myostatin may have therapeutic application in treating muscle wasting diseases such as muscular dystrophy.

Discovery and sequencing:

The gene encoding myostatin was discovered in 1997 by geneticists Se-Jin Lee and Alexandra McPherron who produced a strain of mutant mice that lack the gene. These myostatin "knockout" mice have approximately twice as much muscle as normal mice. These mice were subsequently named "mighty mice".

Naturally occurring deficiencies of myostatin have been identified in cattle by Ravi Kambadur, whippets, and humans; in each case the result is a dramatic increase in muscle mass. A mutation in the 3 UTR of the myostatin gene in Texel sheep creates target sites for the microRNAs miR-1 and miR-206. This is likely to cause the muscular phenotype of this breed of sheep.

Structure and mechanism of action:

Human myostatin consists of two identical subunits, each consisting of 109 (NCBI database claims human myostatin is 375 residues long) amino acid residues. Its total molecular weight is 25.0 kDa. The protein is inactive until a protease cleaves the NH2-terminal, or "pro-domain" portion of the molecule, resulting in the active COOH-terminal dimer.

Myostatin binds to the activin type II receptor, resulting in a recruitment of either coreceptor Alk-3 or Alk-4. This coreceptor then initiates a cell signaling cascade in the muscle, which includes the activation of transcription factors in the SMAD family - SMAD2 and SMAD3. {{|}}These factors then induce myostatin-specific gene regulation. When applied to myoblasts, myostatin inhibits their differentiation into mature muscle fibers.

Myostatin also inhibits Akt, a kinase that is sufficient to cause muscle hypertrophy, in part through the activation of protein synthesis. However, Akt is not responsible for all of the observed muscle hyperthrophic effects which are mediated by myostatin inhibition Thus myostatin acts in two ways: by inhibiting muscle differentiation, and by inhibiting Akt-induced protein synthesis.

product name
jintropin
hygetropin
hygetropin
Riptropin
kigtropin
Igtropin(IGF-1 LR3)
Igtropin
Taitropin
HCG
EPO
MT2
MT2
MT2
HMG
ACE-031
hgh blue/yellow/green/black top
MGF
MGF
MGF
CJC-1295 without DAC
CJC-1295 without DAC
CJC-1295 without DAC
CJC-1295 with DAC
CJC-1295 with DAC
CJC-1295 with DAC
GHRP-2
GHRP-2
GHRP-2
GHRP-6
GHRP-6
GHRP-6
HGH Fragment 176-191
HGH Fragment 176-191
HGH Fragment 176-191
IPAMORELIN
IPAMORELIN
IPAMORELIN
GONADORELIN
GONADORELIN
GONADORELIN
HEXARELIN
HEXARELIN
HEXARELIN
TB-500
TB-500
TB-500
FOLLISTATIN 344(fst-344)
MYOSTATIN
DISP
SELANK
PEG-MGF
PEG-MGF
PEG-MGF
PT-141
PT-141
PT-141

MYOSTATIN Peptide HGH Human Growth Hormone Raw Materials Myostatin Human Growth

Tag:

,


MYOSTATIN Peptide Raw Steroid Powder Myostatin Human Growth Hormone 99.9% Purity Images

 

Send Inquiry

*Email

Please Enter your Email Address

Subject

Inquiry About

Quick question
Please select FAQ

I'm very interested in your products; could you send me some detail reference information?

Please send me detail product specification, thank you!

May I be an agency of your products,and what's yourterms?

We intend to purchase this product, would you please send me the quotation and minimum order quantity?

*Message
I want to buy

For the best results, we recommend including the following details: -Self introduction -Required specifications -Inquire about price/MOQ